Thursday, November 14, 2024

Two year outcome of 2022 intradiscal stem cell procedure at Regenexx Cayman

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Tuesday, July 19, 2022

Allogeneic MSCs

Allogeneic MSCs


The question: is allogeneic stem cell treatment a better option than autologous?

  • Does allogeneic “work” regardless of the mechanism?

  • Does it work as well as autologous?

  • Do the cells work via paracrine only, or are they able to differentiate and engraft?



Human orthopedic clinical studies

  • Transplant Direct. 2017 Sep (Spain)

  • Human study on allogeneic BM

  • N = 30 RCT allo BM vs HA

  • 40 × 10^ 6 = 40M cells

  • Improved cartilage quality 

  • This is allogeneic BM, not WJ.

a Clinical Trial for Safety and Proof-ofConcept With 7 Years of Extended Follow-U



Non-orthopedic clinical studies


Reviews



Dr. Centeno blog entries (chrono order)